Endocrine Abstracts

Introduction: Pregnancy in patients with acromegaly is a rare and challenging medical situation. Here in, we report a patient with acromegaly who presented to us in the 3rdtrimester of pregnancy after endoscopic transnasaltranssphenoidal radical excision of the tumor.Observation: A 36-year-old lady (Gravida 3 Parity 2 Live Birth 2), presented to our outpatient clinic on May 2007 forsuspicion of acromegaly. Clinical examination revealed acromeg...

Introduction: 11β-Hydroxylase deficiency (11β-OHD), caused by CYP11B1 mutations, is characterized by hyporeninemic, hypokalemic hypertension and hyperandrogenism. We studied the mutations of CYP11B1 gene in two patients with classic 11β-OHD.Observations: We present the first case of a 23 year old boy with preliminary diagnosis of 21 β-OHD diagnosed at the age of 10. The patient presented with hypertension and hypokalemia which were ag...

Introduction: Reactive hypoglycemia (RH) is characterized by postprandial hypoglycemic disorder aggravated by the ingestion of high glycaemic index (GI) foods.The aim of this study was to evaluate the effectiveness of dietary regimen recommended for patients with RH.Methods: This interventional prospective study included 20 patients consulted with symptoms suggesting RH, duration of monitoring was one month. Data had been ...

Introduction: Dopamine agonist resistance is rare in prolactinoma (10%). Doses of cabergoline of up to 2.0 mg/week are usually effective in controlling prolactin (PRL) secretion and reducing tumor size. Surgical treatment is rarely indicated.Case report: An 18-year-old female presented in 2002 with a 2-year history of amenorrhea and galactorrhea. Hormonal investigation showed a hyperprolactinemia (4800 mUI/l) with integrity of the other pituitary axis. T...